Webb23 feb. 2024 · New data for tolebrutinib, Sanofi’s investigational oral Bruton’s tyrosine kinase (BTK) inhibitor for the treatment of multiple sclerosis (MS), showed a significant effect on key immune mediators that may drive disease progression within the CNS. Webb31 mars 2024 · Significance A treatment regimen that harnessed the immunostimulatory effects of cyclophosphamide coupled with the inhibition of CSF1R was used to successfully treat several highly aggressive claudin-low TNBC murine mammary tumors and lung metastasis. Competing Interest Statement
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Webb15 sep. 2024 · Protein ubiquitination is a dynamic, tightly controlled, and reversible post-translational modification with the 76 amino-acid protein Ub that is involved in the … WebbUSP22 removes K27-linked ubiquitination on STING through cooperation with USP13. (A) Luciferase activity in indicated sg_DUB 293T cells transfected with an IFNb luciferase … bungalows for sale in fleet lincs
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