Lamp2b
Tīmeklis2024. gada 23. jūn. · lamp2基因9号外显子的剪切差异可致所编码的lamp2蛋白存在lamp2a、lamp2b及lamp2c 3种亚型，区别仅在于溶酶体羧基末端跨膜区域及胞浆短 … TīmeklisPlasmid pCDNAHygro(+)LAMP2B from Dr. Janice Blum's lab contains the insert Lysosome-associated membrane protein 2b and is published in Immunity. 2005 …
Lamp2b
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Tīmeklis2024. gada 22. apr. · Constructing Lamp2b–iRGD: The RVG fragments at both ends of the Lamp2b-RVG plasmid (i.e., enzyme digestion sites BspEI and XhoI) were replaced with iRGD peptides, single-stranded sequences synthesized through annealing of the restriction sites. Then, the sticky ends were, respectively, annealed with a forward … Tīmeklis2024. gada 13. maijs · Recently, RVG has been engineered to exosomal surface via fused protein lysosome-associated membrane glycoprotein 2b (Lamp2b)-RVG in order to achieve neuron-specific targeting . Furthermore, the modified exosomes, with RVG fused to exosomal protein Lamp2b, could efficiently deliver miR-124 to the infarct …
TīmeklisSynthetic peptide corresponding to Human LAMP2B aa 350 to the C-terminus (C terminal) conjugated to keyhole limpet haemocyanin. LAMP2 has 3 distinct isoforms, … Tīmeklis2024. gada 6. sept. · Lamp2b alone or fusion protein was cloned into pcDNA 3.1(-) similarly as described before . For Lamp2b-empty vector construction, the Lamp2b CDS was amplified using corresponding primers, followed by direct clone into pcDNA 3.1(-). For HuR-Lamp2b vector construction, Xho1 and BspE1 cloning sites were …
Lysosome-associated membrane protein 2 (LAMP2), also known as CD107b (Cluster of Differentiation 107b) and Mac-3, is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins. The protein encoded by this gene is a member of a family of membrane glycoproteins. This … Skatīt vairāk The gene for LAMP2 has 9 coding exons and 2 alternate last exons, 9a and 9b. When the last exon is spliced with the alternative exon, it is a variant called LAMP2b, which varies in the last 11 amino acids of its C … Skatīt vairāk Lysosomes are cell organelles found in most animal cells. Their main functions center around breaking down materials and debris in the cell. Some of this is done via acid … Skatīt vairāk • CA77.1 • QX39 Skatīt vairāk • LAMP2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an … Skatīt vairāk LAMP2 has been specifically implicated in tumor cell metastasis. Both LAMP1 and LAMP2 have been found expressed on the surface of … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and … Skatīt vairāk
Tīmeklis2024. gada 15. nov. · 细胞外小囊泡（ sEVs RVG ） 的脑部 神经特异性靶向是通过 将 s EVs膜蛋白lamp2b 和 神经 靶向 性的狂犬病毒糖蛋白衍生肽（RVG） 融合 递呈在 …
Tīmeklis2024. gada 6. sept. · As a proof-of-principle study, RNA-binding protein HuR was fused to the C-terminus of Lamp2b, a membrane protein localized in both exosome and lysosome. The fusion protein was able to be incorporated into the exosomes. Moreover, exosomes engineered with Lamp2b-HuR successfully decreased the abundance of … craft axe throwing logoTīmeklis2024. gada 1. febr. · The pEGFP-C1-RVG-Lamp2b expressing vector was kindly provided by Prof. Matthew J A Wood’ lab from University of Oxford [70]. DNA sequence encoding the glycosylation sequon (GNSTM), E7 Peptide [55] and a glycine-serine spacer were synthesized and subcloned to replace the RVG fragment by XhoI/BspeI … diverticulum in throatTīmeklis2024. gada 15. nov. · 细胞外小囊泡（ sEVs RVG ） 的脑部 神经特异性靶向是通过 将 s EVs膜蛋白lamp2b 和 神经 靶向 性的狂犬病毒糖蛋白衍生肽（RVG） 融合 递呈在 细胞外囊泡 上， 在细胞及动物水平验证了 sEVs RVG-siRNA 的抗病毒能力. 图3： sEVs RVG-siRNA 装载siRNA条件的优化及 其在细胞水平 ... craft a wooden pickaxe