Multiple myeloma cast nephropathy
WebMultiple Myeloma: Cast Nephropathy, VTE, and Neurologic Complications Multiple myeloma accounts for approximately 1% of neoplastic diseases and 13% of hematologic … Web13 nov. 2024 · Myeloma cast nephropathy (CN) is the most common form of monoclonal immunoglobulin-mediated kidney disease, resulting from the precipitation of excessive amounts of monoclonal serum free light chains (sFLC) and causing around 70% of the cases of dialysis-dependent renal failure in multiple myeloma (MM)(Heher et al. 2013; …
Multiple myeloma cast nephropathy
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WebLearn more. Promotional Article Monitoring. ... Light Chain Cast Nephropathy in Multiple Myeloma: Prevalence, Impact and Management Challenges . Fulltext; Metrics; Get Permission; Cite this article; Authors Menè P, Stoppacciaro A, Lai S, Festuccia F. Received 18 February 2024. Web1 sept. 2015 · The underlying pathophysiology is complex and related to multiple mechanisms that include myeloma cast nephropathy, renal amyloidosis, immunoglobulin deposition disease, tubulointerstitial nephritis, hypercalcemia, hypovolemia, plasma cell infiltration, and drug-induced nephrotoxicity. 14 Studies have shown that approximately …
Web8 feb. 2024 · Monoclonal gammopathy of renal significance (MGRS) is a rare heterogeneous group of kidney disorders that encompasses all disorders caused by deposition of monoclonal protein (M-protein) and its light or heavy chain fragments secreted by pre-malignant or non-malignant B-cell clones in patients who do not meet the … WebMultiple myeloma (MM) is a multisystemic plasma cell dyscrasia that primarily affects bone homeostasis, hematopoiesis and renal function [1,2,3].Renal impairment is a common complication of MM and up to 50% of patients with MM present with renal impairment at diagnosis, depending on the definition of renal impairment based on the value of serum …
Web1 aug. 2024 · Myeloma cast nephropathy (MCN) is the most prevalent pathologic diagnosis associated with renal injury, followed by light chain deposition disease and light chain amyloidosis. Several FLC removal techniques have been explored to improve kidney disease in MM but their impact on renal clinical outcomes remains unclear. WebLearn more. Promotional Article Monitoring. ... Light Chain Cast Nephropathy in Multiple Myeloma: Prevalence, Impact and Management Challenges . Fulltext; Metrics; Get …
Web30 oct. 2024 · We included 13 patients with MM or smoldering myeloma (SMM) and ESRD transplanted between 2007 and 2015, including 7 MM with cast nephropathy, 3 with MM-associated amyloid light chain amyloidosis or light chain deposition disease and 3 SMM and compared them with 65 control-matched kidney-transplanted patients.
Web25 feb. 2024 · Multiple myeloma (MM) is the second most common hematologic malignancy that involves monoclonal immunoglobulin (Ig)-producing plasma cells. Due to its multifaceted clinical manifestations and complications, it draws attention to various medical specialties like neurology, nephrology, orthopedics, cardiology, etc. Renal failure (RF) is … happy joker hack apkWeb3 mar. 2024 · Myeloma cast nephropathy (MCN) is a common cause of severe renal impairment in multiple myeloma (MM). The level of free light chain (FLC) that causes MCN varies substantially and there is... happy joe\u0027s maquoketa iaWeb1 sept. 2015 · The underlying pathophysiology is complex and related to multiple mechanisms that include myeloma cast nephropathy, renal amyloidosis, … happy jose