Pomelo drug interactions
WebAsked By : Gerald Winters. Its lineage means that pomelo contains many of the same compounds as grapefruit. One or more substances in grapefruit and grapefruit juice block the action of an enzyme called cytochrome P-450 3A4 (CYP3A4). This enzyme breaks down a wide array of medications, including atorvastatin (Lipitor). WebSep 20, 2024 · Rosuvastatin is a medication that can help lower cholesterol. But it does have some interactions that can raise your risk of side effects. Certain interactions can be managed with lower doses of rosuvastatin. But others may require you to stop taking it. Let your healthcare provider and pharmacist know all medications you’re currently taking.
Pomelo drug interactions
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WebMay 31, 2024 · Seville oranges, limes, and pomelos also contain this chemical and should be avoided if you're taking statins. Does citrus fruit interfere with medications? Yes. Grapefruit and certain other citrus fruits, such as Seville oranges, can interfere with several kinds of prescription medications. Don't take these interactions lightly. Some can cause potentially … WebNational Center for Biotechnology Information
WebApr 1, 2024 · For drugs with narrow therapeutic window, only cyclosporine was confirmed to have drug interactions with fruit juices other than GFJ (i.e., bioavailability of cyclosporine was moderately increased by pomelo juice and moderately decreased by grape juice). WebDec 8, 2024 · Extra care should be taken by pregnant and lactating mothers. Pomelo fruit or juice must be taken only after the doctor’s advice. Interactions with Other Drugs: Consuming pomelo juice with sildenafil (which belongs to the phosphodiesterase5 medicine group) may reduce the bioavailability of sildenafil.
WebNov 1, 2010 · A. The pomelo (also called shaddock, pumelo, pommelo, and Chinese grapefruit) is the largest citrus fruit, ranging from the size of a cantaloupe to that of a large watermelon. Botanists believe that crosses between pomelo and wild orange created … WebT1 - Food-drug interaction of tacrolimus with pomelo, ginger, and turmeric juice in rats. AU - Egashira, Kanoko. AU - Sasaki, Hitoshi. AU - Higuchi, Shun. AU - Ieiri, Ichiro. PY - 2012. Y1 - 2012. N2 - Tacrolimus is a well-known potent immunosuppressant agent, which has various drug-drug or food-drug interactions.
WebJul 21, 2024 · Interaction with grapefruit juice is drug-specific, not drug category-specific. Additionally, the severity of the interaction can vary as well. This is because some interactions are classified as ...
WebApr 13, 1983 · Purpose: The main purpose of this work was to investigate the effect of pummelo juice on the pharmacokinetics of sildenafil after oral administration. Methods: This was a comparative, randomized, two-period, two-treatment, two-sequence, single dose, crossover study investigating the effect of pummelo juice on the pharmacokinetics of … blockfi rewards card reviewWebDrug Interactions with Grapefruit Juice. Medically reviewed by Leigh Ann Anderson, PharmD. ... You should use caution when eating anything made with the seville orange (often used … blockfi rewards visa® signature cardWebJan 18, 2024 · Potential Drug Interactions. Firstly, pomelo contains a significant amount of furanocoumarin . Furanocoumarin is a compound found in some plants that inhibits the … blockfi review