WebApr 1, 2016 · Lipophilic Statin Versus Rosuvastatin (Hydrophilic) Treatment for Heart Failure: a Meta-Analysis and Adjusted Indirect Comparison of Randomised Trials April … WebMay 1, 2024 · The predominantly lipophilic statins (simvastatin, fluvastatin, pitavastatin, lovastatin and atorvastatin) can easily enter cells, whereas hydrophilic statins (rosuvastatin and pravastatin ...
Isoprenoid Metabolism and the Pleiotropic Effects of Statins
WebDo not exceed 10 mg per day of rosuvastatin or ... not support the hypothesis that lipophilic statins (e.g ... are more likely to cause muscle toxicity than hydrophilic ... WebJan 22, 2024 · Lipophilic statins include atorvastatin, simvastatin, lovastatin, fluvastatin, cerivastatin and pitavastatin, while hydrophilic statins include rosuvastatin and … soft palate hurts
Impact of lipophilic vs hydrophilic statins on the clinical ... - Wiley
WebSep 6, 2024 · Lipophilic statins include atorvastatin, simvastatin, lovastatin, fluvastatin, cerivastatin, and pitavastatin, while hydrophilic statins include rosuvastatin and pravastatin . The lipophilicity or hydrophilicity of statins is important for their pharmacokinetics and pharmacodynamics, and these characteristics are considered to be crucial for at least … WebAims: There are insufficient direct comparative studies addressing the impact of the type of statin on their respective efficacy in heart failure (HF). The aim of the current study was to compare the effects of lipophilic (atorvastatin) vs hydrophilic (rosuvastatin) on left ventricular function, inflammatory and fibrosis biomarkers in patients with chronic HF. WebMay 20, 2024 · Drugs can be classified as hydrophilic or lipophilic depending on their ability to dissolve in water or in lipid-containing media. The predominantly lipophilic statins (simvastatin, fluvastatin, pitavastatin, lovastatin and atorvastatin) can easily enter cells, … National Center for Biotechnology Information soft palate is made of